Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013445 | 0.83 | MEN1 (0.60) | KAT6AMEN1KMT2APKMPKLR | |
| SCHEMBL28326534 | 0.83 | HSD17B2 (0.61) | KAT6AMEN1KMT2APKMPKLR | |
| SCHEMBL17849564 | 0.82 | ACLY (0.59) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL9942107 | 0.81 | HSD17B2 (0.61) | KAT6AMEN1KMT2APKMPKLR | |
| SCHEMBL17849561 | 0.81 | KMT2A (0.59) | KAT6AMEN1KMT2APKMPKLR | |
| SCHEMBL13667266 | 0.79 | APP (0.55) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL3075935 | 0.78 | METAP2 (0.57) | KMT2AALDH1A1KEAP1NFE2L2METAP2 | |
| SCHEMBL17852497 | 0.77 | ACLY (0.51) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7267181 | 0.77 | MEN1 (0.51) | KAT6AMEN1KMT2APKMPKLR | |
| SCHEMBL17849556 | 0.76 | HSD17B2 (0.71) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |