Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PYGL | P06737 | 13/20 | 0.39 |
| ▸ | PYGM | P11217 | 13/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266137 | 0.91 | CYP2C9 (0.47) | ALOX15ALDH1A1PYGLPYGMCACNA1B | |
| SCHEMBL7266638 | 0.86 | ALDH1A1 (0.41) | ALOX15ALDH1A1PYGLPYGMCACNA1B | |
| SCHEMBL7275522 | 0.83 | TSHR (0.41) | ALOX15ALDH1A1PYGLPYGMTSHR | |
| SCHEMBL7275922 | 0.83 | CACNA1C (0.55) | ALDH1A1CACNA1BTSHRPOLBHPGD | |
| SCHEMBL3034308 | 0.82 | ALDH1A1 (0.49) | ALOX15ALDH1A1PYGLPYGMTSHR | |
| SCHEMBL7272104 | 0.80 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7267115 | 0.78 | CACNA1B (0.37) | ALDH1A1CACNA1BTSHRHPGDHSD17B10 | |
| SCHEMBL7265623 | 0.77 | CYP2C9 (0.49) | ALDH1A1CACNA1BTSHRHPGDHSD17B10 | |
| SCHEMBL7267980 | 0.76 | PYGL (0.61) | ALOX15PYGLPYGMMAPTKDM4E | |
| SCHEMBL7266662 | 0.76 | ALDH1A1 (0.43) | ALOX15ALDH1A1PYGLPYGMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |