Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | SELL | P14151 | 2/20 | 0.38 |
| ▸ | SELP | P16109 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432374 | 0.86 | ENPP2 (0.43) | OPRM1MAPTPTGDR2ALDH1A1GAA | |
| SCHEMBL6938982 | 0.81 | MAPT (0.39) | OPRM1MAPTPTGDR2ALDH1A1GAA | |
| SCHEMBL9171866 | 0.81 | PTGDR2 (0.39) | MAPTPTGDR2SELLSELPTBXA2R | |
| SCHEMBL1921441 | 0.76 | SELL (0.43) | PTGDR2SELLSELPTBXA2RPTGDR | |
| SCHEMBL2490239 | 0.75 | GAA (0.41) | OPRM1MAPTALDH1A1GAATSHR | |
| SCHEMBL2648376 | 0.72 | GAA (0.46) | MAPTTBXA2RALDH1A1GAATSHR | |
| SCHEMBL3026487 | 0.70 | THRB (0.43) | MAPTALDH1A1GAAAKR1B1NR1H4 | |
| SCHEMBL25264153 | 0.70 | PTGER4 (0.39) | ALDH1A1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL4600049 | 0.70 | GPR3 (0.41) | MAPTGAATSHRCYP1A2 | |
| SCHEMBL31355068 | 0.70 | GPR3 (0.41) | MAPTGAATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |