Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202731 | 0.85 | EGFR (0.45) | RXRARXRBRXRGEGFR | |
| SCHEMBL6938982 | 0.85 | MAPT (0.39) | GAAKMT2AMEN1LMNAOPRM1 | |
| SCHEMBL7432374 | 0.83 | ENPP2 (0.43) | GAALMNAOPRM1TDP1POLB | |
| SCHEMBL8993305 | 0.81 | PLA2G4B (0.43) | LMNATDP1L3MBTL1TSHR | |
| SCHEMBL3026487 | 0.81 | THRB (0.43) | GAAKMT2ACASP3SENP8SENP7 | |
| SCHEMBL2650358 | 0.77 | TAS2R14 (0.43) | ALDH1A1RXRARXRBRXRGMAPT | |
| SCHEMBL2648376 | 0.76 | GAA (0.46) | GAAKMT2AMEN1LMNACA1 | |
| SCHEMBL7269532 | 0.75 | OPRM1 (0.42) | GAAOPRM1TDP1ALDH1A1MAPT | |
| SCHEMBL17456836 | 0.73 | GPR3 (0.44) | GAAKMT2AMEN1LMNAGPR3 | |
| SCHEMBL3044362 | 0.71 | GPR3 (0.46) | GAAKMT2AMEN1LMNAGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560690-B1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2017-03-08 | — | — | EP | disclosed |
| US-9266924-B2 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2560690-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131735-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2011-10-27 | — | — | WO | disclosed |
| EP-2380596-A1 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2011-10-26 | — | — | EP | disclosed |
| EP-1763507-B1 | ALPHA-AMINO ACID DERIVATES WITH ANTIINFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 2010-08-11 | — | — | EP | disclosed |
| US-7635788-B2 | Alpha-amino acid derivatives with antiinflammatory activity | ITALFARMACO SPA (IT) | 2009-12-22 | — | — | US | disclosed |
| US-20080076807-A1 | Alpha-Amino Acid Derivatives with Antiinflammatory Activity | ITALFARMACO SPA (IT) | 2008-03-27 | — | — | US | disclosed |
| EP-1581484-B1 | HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTION | ITALFARMACO SPA (IT) | 2007-07-04 | — | — | EP | disclosed |
| US-7235689-B2 | Hydroxamic acid derivatives having anti-inflammatory action | ITALFARMACO SPA (IT) | 2007-06-26 | — | — | US | disclosed |
| EP-1763507-A2 | ALPHA-AMINO ACID DERIVATES WITH ANTIINFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 2007-03-21 | — | — | EP | disclosed |
| US-20060100285-A1 | Hydroxamic acid derivatives having anti-inflammatory action | ITALFARMACO SPA (IT) | 2006-05-11 | — | — | US | disclosed |
| WO-2006003068-A2 | ALPHA-AMINO ACID DERIVATIVES WITH ANTIINFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | ANXA4, XPNPEP1, ANXA1 | GAA 461/4885KMT2A 1791/4885MEN1 1927/4885 |
| US-20080076807-A1 | Alpha-Amino Acid Derivatives with Antiinflammatory Activity | TNF, NFKBIA, IFNG | GAA 521/4885KMT2A 2165/4885MEN1 659/4885 |
| US-20060100285-A1 | Hydroxamic acid derivatives having anti-inflammatory action | HDAC1, HDAC5, HDAC9 | GAA 79/4885KMT2A 343/4885MEN1 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.