Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285409 | 1.00 | MAPT (0.37) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL7295375 | 1.00 | MAPT (0.37) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL7294807 | 0.80 | REN (0.39) | MAPTKMT2ARECQLMEN1ALDH1A1 | |
| SCHEMBL7288255 | 0.77 | MAPT (0.36) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL7278158 | 0.75 | TSHR (0.35) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL7278156 | 0.75 | TSHR (0.35) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL7316671 | 0.75 | TSHR (0.35) | MAPTMAPK1KMT2AATMNPSR1 | |
| SCHEMBL8604140 | 0.68 | CTSK (0.46) | POLB | |
| SCHEMBL14350312 | 0.68 | LMNA (0.42) | MAPTMAPK1KMT2AATMPOLB | |
| SCHEMBL4491943 | 0.68 | CETP (0.45) | ALDH1A1BLMTSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |