Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780857 | 0.84 | LTA4H (0.44) | PSMB5CTSSPOLBSYK | |
| SCHEMBL9010277 | 0.83 | CTSK (0.45) | CTSKPSMB5CTSSCTSLPOLB | |
| SCHEMBL6064499 | 0.83 | ALDH1A1 (0.50) | CTSK | |
| SCHEMBL6064496 | 0.83 | ALDH1A1 (0.50) | CTSK | |
| SCHEMBL4647195 | 0.80 | ALDH1A1 (0.44) | CTSKCTSSCTSLSYKCTSB | |
| SCHEMBL27711459 | 0.79 | ALDH1A1 (0.49) | CTSK | |
| SCHEMBL4424431 | 0.79 | ALDH1A1 (0.49) | CTSK | |
| SCHEMBL27493616 | 0.79 | LTA4H (0.44) | POLBSYK | |
| SCHEMBL27724812 | 0.78 | SLC15A1 (0.44) | CTSSSYK | |
| SCHEMBL9327919 | 0.78 | CTSK (0.45) | CTSKCTSSCTSLPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007742-A1 | SULFONAMIDES | ZENECA LIMITED (GB) | 1998-02-26 | — | — | WO | disclosed |