Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | PLTP | P55058 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9872238 | 0.94 | ALDH1A1 (0.45) | ALDH1A1TRPV4MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7268936 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP1A2MAPT | |
| SCHEMBL14960379 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7304957 | 0.75 | ALDH1A1 (0.53) | ALDH1A1CYP1A2MAPT | |
| SCHEMBL9618108 | 0.69 | SIGMAR1 (0.50) | ALDH1A1TRPV4MEN1KMT2ACYP1A2 | |
| SCHEMBL12495805 | 0.69 | RORC (0.83) | RORC | |
| SCHEMBL15086878 | 0.68 | ALOX5 (0.74) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL4110096 | 0.68 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| Fumaric Acid SCHEMBL9872705 | 0.68 | HRH2 (0.49) | — | |
| Fumaric Acid SCHEMBL7270229 | 0.68 | HRH2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409048-A2 | Aminoalkyl substituted 2-aminothiazoles and medicines containing them | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |