Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641530 | 0.78 | GPR3 (0.38) | GPR3TNKS2PBRM1HTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7251524 | 0.77 | MYC (0.38) | GPR3TNKS2PBRM1HTR7HTR2B | |
| Ethane SCHEMBL8174121 | 0.77 | GPR3 (0.46) | GPR3ACHELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9073712 | 0.77 | HTR2A (0.40) | HTR7HTR2CALDH1A1ACHEKDM4E | |
| Hydrochloric Acid SCHEMBL6557592 | 0.76 | HTR2A (0.36) | HTR2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL540484 | 0.76 | GPR3 (0.44) | GPR3ACHEMEN1KMT2AATM | |
| SCHEMBL358532 | 0.76 | GPR3 (0.39) | GPR3TNKS2PBRM1HTR7HTR2B | |
| SCHEMBL31338566 | 0.76 | GPR3 (0.39) | GPR3TNKS2PBRM1HTR7HTR2B | |
| SCHEMBL11783880 | 0.76 | HTR2B (0.51) | GPR3TNKS2PBRM1HTR7HTR2B | |
| Hydrochloric Acid SCHEMBL1116212 | 0.76 | GPR3 (0.35) | GPR3TNKS2PBRM1HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270615-A1 | ETHYLENE-BASE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND LUBRICATING OIL COMPOSITIONS CONTAINING THE SAME | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |