Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7944464 | 0.97 | GPR3 (0.42) | GPR3HTR2ACYP19A1HDAC3HDAC4 | |
| Ethane SCHEMBL8174121 | 0.95 | GPR3 (0.46) | GPR3HTR2ACYP19A1HDAC3HDAC4 | |
| Toluene SCHEMBL27459088 | 0.86 | LMNA (0.48) | GPR3HTR2APOLBACHECHRM2 | |
| Hydrochloric Acid SCHEMBL5352654 | 0.82 | HTR2A (0.47) | GPR3HTR2APOLBACHEBCHE | |
| Hydrochloric Acid SCHEMBL7251524 | 0.76 | MYC (0.38) | GPR3HTR2AACHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7270000 | 0.76 | GPR3 (0.36) | GPR3HTR2AACHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4079003 | 0.76 | GPR3 (0.35) | GPR3HTR2APOLB | |
| Hydrochloric Acid SCHEMBL9519060 | 0.73 | ADRA2C (0.37) | — | |
| SCHEMBL6936104 | 0.73 | GPR3 (0.46) | GPR3HTR2ACYP19A1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL3385863 | 0.73 | GPR3 (0.46) | GPR3HTR2ACYP19A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020156-A | Ethylene copolymer and preparation method and application thereof | 中国石油天然气股份有限公司 | 2025-05-20 | — | — | CN | claimed |
| EP-4538307-A1 | POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM | Wanhua Chemical Group Co., Ltd. (CN) | 2025-04-16 | — | — | EP | claimed |
| WO-2025043950-A1 | POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM | 万华化学集团股份有限公司 | 2025-03-06 | — | — | WO | claimed |
| CN-119391327-A | Hot melt adhesive for cigarettes and preparation method thereof | 江苏光辉粘合科技有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118063697-B | Process for preparing cycloolefin-ethylene copolymers | 辽宁鲁华泓锦新材料科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118184847-A | Improved solution polymerization method | 万华化学集团股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118085150-A | Functional vinyl olefin polymer and preparation method thereof | 贝欧亿(山东)新材料有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118063697-A | Process for preparing cycloolefin-ethylene copolymers | 辽宁鲁华泓锦新材料科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-116789883-B | Polyolefin elastomer and application thereof in photovoltaic packaging film | 万华化学集团股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117106118-A | Poly alpha-olefin pour point depressant and preparation method thereof | 中国石油天然气股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| US-6984603-B2 | Organometal catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 2006-01-10 | — | — | US | claimed |
| US-6838533-B2 | Organometal catalyst composition | PHILIPS PETROLEUM COMPANY (US) | 2005-01-04 | — | — | US | claimed |
| US-20040054100-A1 | Production of polyropylene | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2004-03-18 | — | — | US | claimed |
| US-6548441-B1 | Polymerization catalysts comprises an organometal compound, an organoaluminum compound, and a halogenated nickel solid oxide compound; heterogeneous catalysts can lead to form uniform polymer particles that have a high bulk density | PHILLIPS PETROLEUM COMPANY | 2003-04-15 | — | — | US | claimed |
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | claimed |
| EP-0604908-B1 | Process for the polymerisation of alpha-olefins using metallocene compounds having ligands of fluorenylic type | BASELL TECHNOLOGY CO BV (NL) | 2001-09-19 | — | — | EP | claimed |
| CN-1053673-C | Load catalyst system, preparation and application in polymerization of alkene thereof | HOECHST AG (DE) | 2000-06-21 | — | — | CN | claimed |
| US-5731254-A | CATALYST | HOECHST (DE) | 1998-03-24 | — | — | US | claimed |
| CN-1101051-A | Preparation of cycloolefincopolymer | HOECHST AG (DE) | 1995-04-05 | — | — | CN | claimed |
| CN-1096517-A | Load catalyst system, its preparation and the application in olefinic polymerization thereof | HOECHST AG (DE) | 1994-12-21 | — | — | CN | claimed |