Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11206033 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2HDAC3CYP3A4TDP1 | |
| SCHEMBL7263532 | 0.79 | ACE (0.52) | CTSKCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL7265453 | 0.79 | ACE (0.61) | — | |
| Norleucine SCHEMBL7430731 | 0.79 | NOD1 (0.48) | CTSKS1PR1S1PR3CYP1A2CYP2C9 | |
| SCHEMBL6423726 | 0.79 | GGT1 (0.57) | SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL16732115 | 0.77 | TDP1 (0.52) | CTSKCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8084072 | 0.77 | EPHX2 (0.41) | NPSR1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7382823 | 0.77 | NOD1 (0.52) | S1PR1S1PR3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28004307 | 0.77 | TDP1 (0.57) | CTSKMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14307823 | 0.76 | TSHR (0.51) | CTSKCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508727-A | Antihypertensive 2-oxo-imidazolidine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |