SCHEMBL8084072

SCHEMBL8084072

CCCCOC(=O)C(CC(=O)O)NCCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.41
ACHE P22303 8/20 0.40
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
PLA2G2A P14555 1/20 0.37
AKR1B1 P15121 1/20 0.37
ATM Q13315 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17117556 0.84 ACHE (0.44) ACHEPOLBAPEX1CTDSP1TDP1
SCHEMBL19090099 0.78 ALDH1A1 (0.46) ACHEALDH1A1ATMHCAR2
SCHEMBL24021971 0.77 ACHE (0.41) EPHX2ACHE
SCHEMBL7270118 0.77 CTSK (0.46) ALDH1A1TDP1L3MBTL1NPSR1
SCHEMBL14906483 0.77 NOD1 (0.49) EPHX2ACHE
SCHEMBL5359782 0.76 CHRM2 (0.41) EPHX2ACHEALDH1A1NPSR1
SCHEMBL22316954 0.76 EPHX2 (0.43) EPHX2ACHEPLA2G2A
SCHEMBL28568016 0.76 NOD1 (0.56) EPHX2
SCHEMBL12145598 0.76 TDP1 (0.47) EPHX2ALDH1A1POLBAPEX1CTDSP1
SCHEMBL15044810 0.76 NAAA (0.45) EPHX2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000143610-A N-TERTIARY-BUTOXYCARBONYL-3,3'-IMINODIPROPIONATE, ITS PRODUCTION, AND PRODUCTION OF 1-TERTIARY- BUTOXYCARBONYL-4-OXO-3-PIPERIDINECARBOXYLATE KOEI CHEM CO LTD 2000-05-26 JP disclosed