Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL725773 | 0.99 | HTR4 (0.98) | HTR4DRD2DRD4DRD3 | |
| Da-6886 SCHEMBL726214 | 0.88 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| Da-6886 SCHEMBL725324 | 0.88 | HTR4 (0.98) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL506210 | 0.87 | HTR4 (0.78) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL724942 | 0.87 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL724283 | 0.86 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL725813 | 0.85 | HTR4 (0.98) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7389964 | 0.85 | HTR4 (0.78) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL725807 | 0.84 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7389801 | 0.84 | HTR4 (0.77) | HTR4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560955-B1 | NOVEL BENZAMIDE DERIVATIVES | DONG A PHARM CO LTD (KR) | 2016-06-29 | — | — | EP | claimed |
| US-9221790-B2 | Benzamide derivatives | DONG-A PHARM. CO., LTD. (KR) | 2015-12-29 | — | — | US | claimed |
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM. CO., LTD. (KR) | 2013-04-04 | — | — | US | claimed |
| EP-2560955-A2 | NOVEL BENZAMIDE DERIVATIVES | Dong-A Pharm.Co., Ltd. (KR) | 2013-02-27 | — | — | EP | claimed |
| WO-2011132901-A2 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM.CO., LTD. (KR) | 2011-10-27 | — | — | WO | claimed |
| EP-2560955-B1 | NOVEL BENZAMIDE DERIVATIVES | DONG A PHARM CO LTD (KR) | 2016-06-29 | — | — | EP | disclosed |
| US-9221790-B2 | Benzamide derivatives | DONG-A PHARM. CO., LTD. (KR) | 2015-12-29 | — | — | US | disclosed |
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM. CO., LTD. (KR) | 2013-04-04 | — | — | US | disclosed |
| EP-2560955-A2 | NOVEL BENZAMIDE DERIVATIVES | Dong-A Pharm.Co., Ltd. (KR) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011132901-A2 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM.CO., LTD. (KR) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | HTR4, GPR4, HTR5A | HTR4 1/4885DRD2 570/4885DRD4 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.