Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278260 | 0.90 | ALDH1A1 (0.54) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7276029 | 0.89 | RAB9A (0.56) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7270653 | 0.86 | CYP2D6 (0.56) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7288972 | 0.86 | GABRA1 (0.47) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7278463 | 0.83 | CYP2D6 (0.53) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7269469 | 0.83 | CYP2D6 (0.60) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7269463 | 0.83 | CYP2D6 (0.60) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7271039 | 0.83 | CYP2D6 (0.60) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7277894 | 0.82 | CYP2D6 (0.62) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7270646 | 0.80 | RAB9A (0.54) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |