Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538263 | 0.98 | TSHR (0.68) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL11539710 | 0.86 | L3MBTL1 (0.51) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL11543765 | 0.86 | KDM4E (0.57) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL12535900 | 0.80 | TSHR (0.69) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL13821340 | 0.80 | KDM4E (0.67) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL25010832 | 0.80 | KDM4E (1.00) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL25010831 | 0.80 | KDM4E (1.00) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL11537591 | 0.80 | KDM4E (1.00) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| SCHEMBL4580390 | 0.79 | CYP2D6 (1.00) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4350444 | 0.79 | KDM4E (0.65) | KDM4ETSHRCYP2D6HIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430332-A | ANGINA PECTORIS | CENTRE EUROPEEN DE RECHERCHES MAUVERNAY (FR) | 1984-02-07 | — | — | US | disclosed |
| EP-0031771-A1 | 1-(2-Propynyloxy)-2-amino-3-propanol ethers, their preparation and pharmaceutical composition containing them | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1981-07-08 | — | — | EP | disclosed |
| US-4170653-A | Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers | Ayerst McKenna and Harrison Limited (CA) | 1979-10-09 | — | — | US | disclosed |
| US-4060613-A | ANTIDEPRESSANT | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-29 | — | — | US | disclosed |