Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642833 | 0.86 | HSD17B10 (0.67) | ALDH1A1MTNR1AMTNR1BHSD17B10TP53 | |
| SCHEMBL10642415 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MTNR1AMTNR1BHSD17B10TP53 | |
| SCHEMBL22864069 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TP53KDM4ETSHR | |
| SCHEMBL9688747 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MTNR1AMTNR1BHSD17B10TP53 | |
| SCHEMBL11712397 | 0.76 | ADRB2 (0.48) | ALDH1A1HSD17B10TP53KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL11035276 | 0.75 | ADRB2 (0.48) | ALDH1A1HSD17B10TP53KDM4ETSHR | |
| SCHEMBL7281232 | 0.75 | HTR2A (0.50) | ALDH1A1HSD17B10TP53KDM4ELMNA | |
| SCHEMBL10640768 | 0.74 | ADRB2 (0.67) | ALDH1A1HSD17B10TP53KDM4ETSHR | |
| SCHEMBL9688803 | 0.74 | MTNR1A (0.44) | ALDH1A1MTNR1AMTNR1BHSD17B10TP53 | |
| SCHEMBL10641574 | 0.74 | ADRB2 (0.58) | ALDH1A1HSD17B10TP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4868306-A | Compounds | FISONS PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| US-4791216-A | Para ethyl amino phenol pharmaceutical compounds | FISONS PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| US-4657929-A | Compounds | FISONS PLC (GB) | 1987-04-14 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |