Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899527 | 0.71 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL5489842 | 0.71 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL28929632 | 0.70 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL27561926 | 0.68 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL28791221 | 0.65 | FDPS (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL27363350 | 0.63 | SMPD1 (0.43) | ALDH1A1 | |
| SCHEMBL11001541 | 0.62 | ODC1 (0.50) | — | |
| SCHEMBL3111870 | 0.59 | — | — | |
| SCHEMBL28047148 | 0.59 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL8601347 | 0.59 | ARG1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |