Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007753 | 0.76 | GGT1 (0.33) | GGT1KDM4E | |
| SCHEMBL7372440 | 0.73 | ARG1 (0.33) | ARG1GGT1KDM4E | |
| Hydrochloric Acid SCHEMBL8555890 | 0.72 | NOS2 (0.37) | GGT1KDM4E | |
| Hydrochloric Acid SCHEMBL8555892 | 0.72 | NOS2 (0.37) | GGT1KDM4E | |
| SCHEMBL382142 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1A | |
| SCHEMBL6007078 | 0.69 | CA2 (0.37) | SMN1; SMN2 | |
| SCHEMBL7651608 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1A | |
| Hydrochloric Acid SCHEMBL382912 | 0.68 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1A | |
| SCHEMBL825611 | 0.64 | SMN1; SMN2 (0.42) | ARG1ARG2SMN1; SMN2HIF1AGGT1 | |
| SCHEMBL31603922 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |