Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275127 | 0.91 | TSHR (0.50) | ALDH1A1TSHRPOLBGALK1HSD17B10 | |
| SCHEMBL3034308 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL7267559 | 0.87 | TSHR (0.44) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL9765712 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL7275653 | 0.86 | ALOX15 (0.41) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL7267267 | 0.81 | CACNA1D (0.58) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL7272404 | 0.79 | TSHR (0.54) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL7265615 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBHSD17B10KDM4E | |
| SCHEMBL3026759 | 0.78 | KDM4E (0.62) | ALDH1A1TSHRHSD17B10KDM4EHPGD | |
| SCHEMBL7266025 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRPOLBHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |