Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 9/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825330 | 0.95 | CCR3 (0.63) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL4499901 | 0.90 | CCR3 (0.69) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL4499239 | 0.90 | CCR3 (0.69) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL544141 | 0.89 | CCR3 (0.67) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL3107807 | 0.89 | CCR3 (0.71) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| Hydrochloric Acid SCHEMBL6092095 | 0.87 | CCR3 (0.65) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL15045173 | 0.86 | CCR3 (0.55) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL7371344 | 0.86 | SIGMAR1 (0.67) | CCR3ACHEBCHEDRD2HTR2A | |
| SCHEMBL6846812 | 0.86 | CCR3 (0.68) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL4789907 | 0.84 | CCR3 (0.61) | CCR3ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117669-A1 | BENZISOSELENAZOLONE-CONTAINING DONEPEZIL ANALOG | 中山大学 (CN) | 2014-08-07 | — | — | WO | disclosed |
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5190951-A | Inhibitors of acetylcholinesterase, treatment of senile dementia | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |