Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.54 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8409067 | 0.92 | F2 (0.51) | ITGB3ITGA2BTACR3F2PRSS1 | |
| Hydrochloric Acid SCHEMBL8410566 | 0.92 | ITGB3 (0.61) | ITGB3ITGA2BF2PRSS1TPSAB1 | |
| Hydrochloric Acid SCHEMBL7272726 | 0.86 | F2 (0.49) | ITGB3ITGA2BTACR3F2PRSS1 | |
| SCHEMBL8410417 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8410226 | 0.81 | LTA4H (0.51) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8863340 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8408077 | 0.80 | F2 (0.50) | ITGB3ITGA2BF2PRSS1TPSAB1 | |
| Hydrochloric Acid SCHEMBL8407670 | 0.80 | L3MBTL1 (0.61) | ITGB3ITGA2BF2PRSS1TPSAB1 | |
| Hydrochloric Acid SCHEMBL8410466 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL8409985 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BF2PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |