Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282618 | 0.89 | ALDH1A1 (0.34) | HCRTR1HCRTR2SIGMAR1ALDH1A1TP53 | |
| SCHEMBL7275231 | 0.84 | CHRNB4 (0.37) | CHRM3ELANESIGMAR1ALDH1A1TP53 | |
| SCHEMBL7275948 | 0.84 | CHRNB4 (0.37) | CHRM3ELANESIGMAR1ALDH1A1TP53 | |
| SCHEMBL7279479 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL7274612 | 0.83 | HRH3 (0.36) | HRH3SLC6A4HCRTR1HCRTR2ELANE | |
| SCHEMBL7276617 | 0.83 | FAAH (0.37) | CHRM3ELANESIGMAR1TP53CYP1A2 | |
| SCHEMBL7284852 | 0.82 | HRH3 (0.40) | HRH3SLC6A4HCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL7283004 | 0.82 | SLC6A4 (0.40) | HRH3SLC6A4CYP1A2 | |
| SCHEMBL7281843 | 0.81 | EHMT2 (0.35) | ALDH1A1TP53MDM2 | |
| SCHEMBL7283379 | 0.80 | SSTR5 (0.41) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |