Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275948 | 0.92 | CHRNB4 (0.37) | MGLLKMT2AMEN1SIGMAR1CHRNB4 | |
| SCHEMBL7275231 | 0.92 | CHRNB4 (0.37) | MGLLKMT2AMEN1SIGMAR1CHRNB4 | |
| SCHEMBL7276617 | 0.89 | FAAH (0.37) | SSTR5MGLLKMT2AMEN1SIGMAR1 | |
| SCHEMBL7282618 | 0.86 | ALDH1A1 (0.34) | KMT2AMEN1HTTSIGMAR1CHRNB4 | |
| SCHEMBL7276128 | 0.86 | LTA4H (0.46) | SSTR5MGLLLTA4HEPHX2HRH3 | |
| SCHEMBL7281067 | 0.85 | MGLL (0.41) | SSTR5MGLLLTA4HEPHX2HRH3 | |
| SCHEMBL7274552 | 0.85 | TK1 (0.34) | — | |
| SCHEMBL7276102 | 0.83 | FAAH (0.38) | MGLLSIGMAR1CHRNB4CHRNA3 | |
| SCHEMBL7280970 | 0.83 | TEAD3 (0.36) | LTA4HKMT2AMEN1CHRNB4CHRNA3 | |
| SCHEMBL7282778 | 0.82 | FAAH (0.39) | MGLLCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |