Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275478 | 0.93 | CHRNB4 (0.39) | ALDH1A1MEN1KMT2ASIGMAR1GAA | |
| SCHEMBL7275324 | 0.93 | CHRNB4 (0.39) | ALDH1A1MEN1KMT2ASIGMAR1GAA | |
| SCHEMBL7283442 | 0.92 | GAA (0.39) | MEN1KMT2ASIGMAR1GAAGBA1 | |
| SCHEMBL7272672 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL7273849 | 0.87 | TSHR (0.41) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7283004 | 0.86 | SLC6A4 (0.40) | — | |
| SCHEMBL7283123 | 0.85 | TEAD3 (0.42) | MEN1KMT2AGAAGBA1 | |
| SCHEMBL7276128 | 0.83 | LTA4H (0.46) | MEN1KMT2AHTT | |
| SCHEMBL7281899 | 0.82 | CASP3 (0.43) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL7281928 | 0.82 | F2 (0.36) | ALDH1A1MEN1KMT2ASIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |