SCHEMBL727419

SCHEMBL727419

Cc1cc([S+]([O-])c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
PTGS1 P23219 7/20 0.35
PTGS2 P35354 7/20 0.35
ALOX5 P09917 6/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ACHE P22303 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2B6 P20813 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6233426 0.81 SHBG (0.36) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL13088296 0.78 CA1 (0.55) CA1CA2ESR1ESR2ALDH1A1
Hydrochloric Acid SCHEMBL11333589 0.76 CA1 (0.52) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL757657 0.76 CA1 (0.52) CA1CA2ESR1ESR2ALDH1A1
Hydrochloric Acid SCHEMBL3646825 0.74 CA1 (0.50) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL72006 0.73 TP53 (0.50) ESR1ESR2ALDH1A1KDM4EMAPT
SCHEMBL10022955 0.72 CA1 (0.48) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL10456842 0.70 CA1 (0.41) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL11390703 0.69 ALDH1A1 (0.40) ALDH1A1ACHE
SCHEMBL5363872 0.69 BACE1 (0.50) CA1CA2ALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1938379-B Impact-modified compositions and methods GEN ELECTRIC 2012-05-16 CN claimed
JP-4801308-B2 2011-10-26 JP claimed
US-7510768-B2 Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein EASTMAN CHEMICAL COMPANY (US) 2009-03-31 US claimed
EP-1569795-B1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEM CO (US) 2008-09-03 EP claimed
EP-1575774-B1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEM CO (US) 2008-08-13 EP claimed
EP-1913053-A1 THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2008-04-23 EP claimed
EP-1713862-B1 IMPACT-MODIFIED COMPOSITIONS AND METHOD GEN ELECTRIC (US) 2008-01-23 EP claimed
US-20070112144-A1 Method for decreasing gloss in molded article CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-17 US claimed
CN-1938379-A Impact-modified compositions and methods GEN ELECTRIC (US) 2007-03-28 CN claimed
WO-2007001571-A1 THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2007-01-04 WO claimed
WO-2004048090-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
US-20040101678-A1 Thermoplastic article having a decorative material embedded therein EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
US-20040101687-A1 Articles of manufacture incorporating polyester/polycarbonate blends EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
EP-1274781-A2 POLYCARBONATE COMPOSITION RESISTANT TO GAMMA RADIATION Bayer Corporation (US) 2003-01-15 EP claimed
EP-1196491-A1 POLYCARBONATE COMPOSITION RESISTANT TO GAMMA RADIATION Bayer Corporation (US) 2002-04-17 EP claimed
WO-2001074934-A2 POLYCARBONATE COMPOSITION RESISTANT TO GAMMA RADIATION BAYER CORPORATION (US) 2001-10-11 WO claimed
US-6197854-B1 Polycarbonate composition resistant to gamma radiation BAYER CORPORATION 2001-03-06 US claimed
US-6197853-B1 Polycarbonate composition resistant to gamma radiation BAYER CORPORATION 2001-03-06 US claimed
WO-2001002474-A1 POLYCARBONATE COMPOSITION RESISTANT TO GAMMA RADIATION BAYER CORPORATION (US) 2001-01-11 WO claimed
US-5342905-A Process for making an ester containing polyether sulfone MILES INC. (US) 1994-08-30 US claimed