Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274477 | 0.81 | ACHE (0.43) | KMT2AMEN1BCHEACHECHRM1 | |
| SCHEMBL7283362 | 0.81 | L3MBTL1 (0.45) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9693861 | 0.81 | ALDH1A1 (0.54) | KMT2AMEN1KDM4EELANEALDH1A1 | |
| SCHEMBL7272513 | 0.81 | HSD17B10 (0.54) | KMT2AMEN1KDM4EELANEALDH1A1 | |
| SCHEMBL29249050 | 0.81 | KMT2A (0.53) | KMT2AMEN1KDM4EELANEALDH1A1 | |
| SCHEMBL29249068 | 0.78 | CYP1A2 (0.45) | KMT2AMEN1KDM4EELANEALDH1A1 | |
| SCHEMBL29249069 | 0.75 | KMT2A (0.51) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL29249091 | 0.75 | MEN1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL29249095 | 0.75 | MEN1 (0.51) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL29249066 | 0.75 | MEN1 (0.51) | KMT2AMEN1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |