Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.43 |
| ▸ | BCHE | P06276 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283362 | 0.89 | L3MBTL1 (0.45) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL29249103 | 0.81 | ESR1 (0.52) | ACHEMEN1KMT2A | |
| SCHEMBL7274459 | 0.81 | KMT2A (0.41) | ACHEBCHEMEN1KMT2ACHRM1 | |
| SCHEMBL5014974 | 0.74 | PDE1A (0.52) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL29249095 | 0.69 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL29249036 | 0.69 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL29249055 | 0.65 | MEN1 (0.52) | ACHEMEN1KMT2AC1R | |
| SCHEMBL7283059 | 0.65 | KDM4E (0.46) | ACHEMEN1KMT2A | |
| SCHEMBL8133213 | 0.64 | PDE3B (0.50) | ACHEMEN1KMT2A | |
| SCHEMBL9876043 | 0.64 | ACHE (0.63) | ACHEBCHEKMT2ACHRM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |