Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 4/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276617 | 0.87 | FAAH (0.37) | — | |
| SCHEMBL7275948 | 0.86 | CHRNB4 (0.37) | — | |
| SCHEMBL7275231 | 0.86 | CHRNB4 (0.37) | — | |
| SCHEMBL7283379 | 0.85 | SSTR5 (0.41) | — | |
| SCHEMBL7282618 | 0.84 | ALDH1A1 (0.34) | — | |
| SCHEMBL7284042 | 0.83 | ATM (0.36) | — | |
| SCHEMBL8881170 | 0.83 | ALOX12 (0.37) | ALOX12 | |
| SCHEMBL7282844 | 0.83 | ALOX12 (0.37) | ALOX12TEAD1TEAD3 | |
| SCHEMBL8881174 | 0.83 | ALOX12 (0.37) | ALOX12 | |
| SCHEMBL7275578 | 0.83 | ALOX12 (0.37) | ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |