Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281678 | 0.90 | HTR1A (0.42) | MAOANAMPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7274708 | 0.89 | CHRM4 (0.42) | CCR3MAOANAMPTSIGMAR1CHRM4 | |
| Methyl Alcohol SCHEMBL8879759 | 0.89 | HTR1A (0.40) | CCR3NAMPTCHRM4HTR1AKDM1A | |
| SCHEMBL7275535 | 0.89 | CCR3 (0.43) | CCR3MAOANAMPTSIGMAR1CHRM4 | |
| SCHEMBL7274088 | 0.88 | HTR1A (0.42) | NAMPTALDH1A1TSHRSMN1; SMN2OPRM1 | |
| SCHEMBL7282394 | 0.87 | ITGB3 (0.44) | CHRM4ALDH1A1TSHRSMN1; SMN2OPRM1 | |
| SCHEMBL7284039 | 0.87 | ITGB3 (0.42) | CHRM4ALDH1A1TSHRSMN1; SMN2OPRM1 | |
| Water SCHEMBL7273367 | 0.85 | F10 (0.45) | — | |
| SCHEMBL7277147 | 0.84 | ASAH1 (0.42) | CHRM4ALDH1A1TSHRSMN1; SMN2OPRM1 | |
| SCHEMBL7280929 | 0.84 | KDM1A (0.42) | MAOANAMPTCHRM4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |