Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278834 | 0.92 | HTR1A (0.39) | HTR1AKAT6ACHRM4NAMPTPREP | |
| SCHEMBL8879756 | 0.90 | HTR1A (0.38) | HTR1AKAT6ACHRM4NAMPTPREP | |
| SCHEMBL7281678 | 0.90 | HTR1A (0.42) | HTR1ANAMPTCHRM3DRD2DRD3 | |
| SCHEMBL7274964 | 0.89 | CCR3 (0.44) | HTR1ACHRM4NAMPTKDM1AHDAC6 | |
| SCHEMBL7284946 | 0.86 | F10 (0.48) | HTR1A | |
| SCHEMBL7273443 | 0.86 | HTR1A (0.42) | HTR1ACHRM3DRD2 | |
| SCHEMBL7274708 | 0.85 | CHRM4 (0.42) | HTR1ACHRM4NAMPTKDM1AHDAC6 | |
| SCHEMBL7273369 | 0.85 | MAOA (0.38) | HTR1ACHRM4NAMPTDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7272974 | 0.85 | F10 (0.51) | — | |
| SCHEMBL7284718 | 0.83 | HTR1A (0.42) | HTR1ANAMPTCHRM3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |