Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273515 | 0.93 | MTNR1A (0.38) | OPRM1OPRD1LMNANAMPT | |
| SCHEMBL7275524 | 0.93 | ITGB3 (0.41) | CHRM4ITGB3ITGA2BOPRM1OPRD1 | |
| SCHEMBL7275558 | 0.86 | MTNR1A (0.38) | ITGB3ITGA2BOPRM1OPRD1NAMPT | |
| SCHEMBL7286655 | 0.83 | NAMPT (0.42) | CHRM4ITGB3ITGA2BNAMPTRAB9A | |
| SCHEMBL7273510 | 0.82 | XIAP (0.32) | — | |
| SCHEMBL7272741 | 0.82 | NAMPT (0.42) | CHRM4OPRM1OPRD1LMNANAMPT | |
| SCHEMBL7276523 | 0.82 | ITGB3 (0.43) | CHRM4ITGB3ITGA2BOPRM1OPRD1 | |
| SCHEMBL7281190 | 0.81 | NAMPT (0.42) | CHRM4ITGB3ITGA2BOPRM1OPRD1 | |
| SCHEMBL7286896 | 0.81 | NAMPT (0.39) | CHRM4ITGB3ITGA2BSMN1; SMN2NAMPT | |
| SCHEMBL7276437 | 0.81 | ITGB3 (0.40) | CHRM4ITGB3ITGA2BOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |