Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273515 | 0.93 | MTNR1A (0.38) | MTNR1AHTR1ACTSLCTSBCTSK | |
| SCHEMBL7275524 | 0.93 | ITGB3 (0.41) | MTNR1AITGB3ITGA2BNAMPTOPRM1 | |
| Water SCHEMBL7275052 | 0.87 | ITGB3 (0.38) | MTNR1AHTR1AITGB3ITGA2BDRD4 | |
| SCHEMBL7275082 | 0.86 | CHRM4 (0.38) | ITGB3ITGA2BNAMPTOPRM1OPRD1 | |
| Water SCHEMBL7284228 | 0.85 | ITGB3 (0.40) | MTNR1AHTR1AITGB3ITGA2BITGAV | |
| SCHEMBL7274663 | 0.85 | ITGB3 (0.40) | MTNR1AHTR1AITGB3ITGA2BOPRM1 | |
| Water SCHEMBL7281668 | 0.84 | ITGB3 (0.38) | MTNR1AHTR1AITGB3ITGA2BOPRM1 | |
| SCHEMBL7287003 | 0.84 | ITGB3 (0.43) | MTNR1AHTR1AITGB3ITGA2BDRD4 | |
| SCHEMBL7282801 | 0.84 | KMT2A (0.37) | MTNR1AHTR1AITGB3ITGA2B | |
| SCHEMBL7284870 | 0.82 | ITGB3 (0.41) | MTNR1AHTR1AITGB3ITGA2BDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |