Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20899861 | 0.78 | POLQ (0.46) | MAPK1NPSR1PKMGAALMNA | |
| SCHEMBL5693351 | 0.76 | MAPK1 (0.43) | MAPK1NPSR1PKMGAAALDH1A1 | |
| SCHEMBL20899886 | 0.76 | MAPK1 (0.47) | MAPK1NPSR1PKMGAAALDH1A1 | |
| SCHEMBL7304678 | 0.76 | SLC6A3 (0.35) | MAPK1NPSR1PKMGAAALDH1A1 | |
| SCHEMBL7094417 | 0.74 | MAPK1 (0.44) | MAPK1NPSR1PKMGAAALDH1A1 | |
| SCHEMBL16578235 | 0.71 | OPRD1 (0.34) | MAPK1NPSR1SLC6A3KDM4CGPR142 | |
| SCHEMBL21838187 | 0.71 | OPRD1 (0.34) | MAPK1NPSR1SLC6A3KDM4CGPR142 | |
| SCHEMBL9565308 | 0.70 | KDM4E (0.44) | MAPK1NPSR1PKMSLC6A3KDM4E | |
| SCHEMBL5535517 | 0.69 | GPR142 (0.40) | MAPK1NPSR1PKMSLC6A3KDM4E | |
| SCHEMBL14561302 | 0.69 | GPR142 (0.40) | MAPK1NPSR1PKMSLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |