Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275089 | 0.78 | MAPK1 (0.41) | KMT2AMEN1OPRD1PKMLMNA | |
| SCHEMBL5693351 | 0.75 | MAPK1 (0.43) | KMT2AMEN1OPRD1PKMLMNA | |
| SCHEMBL7094417 | 0.73 | MAPK1 (0.44) | KMT2AMEN1OPRD1PKMLMNA | |
| SCHEMBL8263373 | 0.72 | ALDH1A1 (0.58) | POLQKMT2AMEN1LMNAROCK2 | |
| SCHEMBL20899886 | 0.72 | MAPK1 (0.47) | KMT2AMEN1OPRD1PKMLMNA | |
| SCHEMBL5071504 | 0.72 | LMNA (0.48) | POLQKMT2AMEN1PKMLMNA | |
| SCHEMBL11438169 | 0.72 | ROCK2 (0.47) | POLQKMT2AMEN1LMNATP53 | |
| SCHEMBL20346360 | 0.70 | POLQ (0.49) | POLQKMT2AMEN1LMNATP53 | |
| SCHEMBL1760632 | 0.69 | KMT2A (0.58) | POLQKMT2AMEN1LMNANPSR1 | |
| SCHEMBL7830345 | 0.68 | KMT2A (0.56) | POLQKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075394-A1 | COMPOUNDS FOR TREATMENT OF EMOTIONAL/PSYCHOLOGICAL SYMPTOMS IN FRAGILE X SYNDROME | VANDERKLISH PETER (US) | 2019-04-18 | — | — | WO | disclosed |