Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946472 | 0.77 | ATM (0.44) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL2115832 | 0.77 | F10 (0.59) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL25541378 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL8461478 | 0.69 | CA12 (0.42) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6282109 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL14280098 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL1727656 | 0.68 | LTA4H (0.60) | ALDH1A1MAPTLMNAHTTMGLL | |
| SCHEMBL1494699 | 0.68 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL15328181 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL8718494 | 0.67 | HCAR1 (0.51) | ALDH1A1MAPTLMNAHTTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418696-A2 | Derivatives of aminoacids | MERCK PATENT GmbH (DE) | 1991-03-27 | — | — | EP | disclosed |
| EP-0401507-A1 | Cyclic agonists of tachykinin | MERCK PATENT GmbH (DE) | 1990-12-12 | — | — | EP | disclosed |
| EP-0284942-A2 | Amino-acid derivatives | MERCK PATENT GmbH (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0272444-A2 | Renin-inhibiting peptides | MERCK PATENT GmbH (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0264795-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-27 | — | — | EP | disclosed |