Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281991 | 0.94 | KMT2A (0.36) | KMT2AL3MBTL1MTNR1ASIGMAR1SCN9A | |
| SCHEMBL7271758 | 0.94 | SIGMAR1 (0.38) | KMT2AL3MBTL1MTNR1ASIGMAR1SCN9A | |
| SCHEMBL7276437 | 0.93 | ITGB3 (0.40) | KMT2AL3MBTL1SIGMAR1SCN9AITGB3 | |
| Water SCHEMBL7275052 | 0.87 | ITGB3 (0.38) | MTNR1AITGB3ITGA2BHTR1ASLC6A5 | |
| SCHEMBL7284329 | 0.87 | ACACB (0.41) | SIGMAR1ITGB3ITGA2BHTR1A | |
| SCHEMBL7272709 | 0.85 | SIGMAR1 (0.38) | KMT2AL3MBTL1MTNR1ASIGMAR1HTR1A | |
| SCHEMBL7286501 | 0.85 | KDM4E (0.43) | MTNR1ASIGMAR1ITGB3ITGA2BHTR1A | |
| Water SCHEMBL7275243 | 0.85 | KMT2A (0.40) | KMT2AL3MBTL1SIGMAR1SCN9AHTR1A | |
| SCHEMBL7277905 | 0.84 | KDM4E (0.41) | SIGMAR1ITGB3ITGA2BHTR1A | |
| SCHEMBL7275558 | 0.84 | MTNR1A (0.38) | MTNR1AITGB3ITGA2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |