Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282778 | 0.95 | FAAH (0.39) | FAAHMGLLCHRNB4CHRNA3GSK3A | |
| SCHEMBL7275231 | 0.90 | CHRNB4 (0.37) | FAAHMGLLCHRNB4CHRNA3GSK3A | |
| SCHEMBL7275948 | 0.90 | CHRNB4 (0.37) | FAAHMGLLCHRNB4CHRNA3GSK3A | |
| SCHEMBL7272646 | 0.90 | GSK3A (0.35) | GSK3AGSK3BSIGMAR1 | |
| SCHEMBL7276617 | 0.87 | FAAH (0.37) | FAAHMGLLCHRNB4CHRNA3GSK3A | |
| SCHEMBL7283097 | 0.86 | HRH3 (0.40) | CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL7275757 | 0.84 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL7282618 | 0.84 | ALDH1A1 (0.34) | FAAHCHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL7273271 | 0.83 | ALDH1A1 (0.40) | GSK3AGSK3B | |
| SCHEMBL7283379 | 0.83 | SSTR5 (0.41) | MGLLCHRNB4CHRNA3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |