Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277794 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7275114 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7283315 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7283263 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7282036 | 0.86 | MMP2 (0.41) | ITGB3ITGA2B | |
| SCHEMBL7280353 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7272750 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7275930 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7283230 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7281127 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | claimed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | claimed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | claimed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |