Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.53 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275930 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7272750 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7275215 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BNQO2PRSS1F2 | |
| SCHEMBL7282191 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BTMPRSS15PRSS1 | |
| SCHEMBL7276253 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7275114 | 0.84 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7273299 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7283093 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7282034 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BNQO2PRSS1PRSS2 | |
| SCHEMBL7273000 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |