Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279509 | 0.84 | MMP12 (0.46) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL3703323 | 0.77 | MMP12 (0.60) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL7684870 | 0.76 | EDNRA (0.57) | — | |
| SCHEMBL24775966 | 0.74 | MMP12 (0.60) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL9920485 | 0.74 | MMP12 (0.64) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL4135845 | 0.74 | MMP12 (0.53) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL4134290 | 0.74 | MMP12 (0.56) | MMP12ALDH1A1PARP1MAPTACLY | |
| SCHEMBL1992570 | 0.73 | EDNRA (0.34) | — | |
| SCHEMBL7438336 | 0.73 | EDNRA (0.39) | — | |
| SCHEMBL16792458 | 0.73 | MMP12 (0.52) | MMP12ALDH1A1PARP1MAPTACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445467-A1 | Renin inhibitors and antiviral agents | Beecham Group p.l.c. (GB) | 1991-09-11 | — | — | EP | disclosed |
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |