Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684870 | 0.80 | EDNRA (0.57) | EDNRAPTGS1PTGS2 | |
| SCHEMBL7436742 | 0.73 | APP (0.31) | APP | |
| SCHEMBL7276282 | 0.73 | MMP12 (0.48) | — | |
| SCHEMBL11085866 | 0.72 | APP (0.36) | EDNRAAPP | |
| SCHEMBL7428737 | 0.72 | FFAR1 (0.44) | — | |
| SCHEMBL27677819 | 0.71 | PTGS1 (0.47) | EDNRAPTGS1PTGS2 | |
| SCHEMBL27684645 | 0.71 | PTGS1 (0.47) | EDNRAPTGS1PTGS2 | |
| SCHEMBL1992570 | 0.70 | EDNRA (0.34) | EDNRA | |
| SCHEMBL1205124 | 0.70 | HSD17B10 (0.61) | EDNRAAPP | |
| SCHEMBL7448758 | 0.70 | KMT2A (0.39) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |