Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985762 | 0.80 | PRSS1 (0.42) | PRSS1PRSS2PRSS3 | |
| SCHEMBL15772000 | 0.79 | PRSS1 (0.32) | PRSS1PRSS2PRSS3 | |
| SCHEMBL14898222 | 0.76 | PRSS1 (0.38) | PRSS1PRSS2PRSS3 | |
| SCHEMBL1992569 | 0.74 | SMN1; SMN2 (0.42) | PRSS1PRSS2PRSS3 | |
| SCHEMBL7276282 | 0.73 | MMP12 (0.48) | — | |
| SCHEMBL7684870 | 0.73 | EDNRA (0.57) | EDNRA | |
| SCHEMBL2110715 | 0.70 | HDAC1 (0.36) | PRSS1PRSS2PRSS3 | |
| SCHEMBL7438336 | 0.70 | EDNRA (0.39) | EDNRA | |
| SCHEMBL14879763 | 0.70 | PRSS1 (0.41) | PRSS1PRSS2PRSS3 | |
| SCHEMBL2919576 | 0.69 | PRSS1 (0.38) | PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079103-A1 | SPIROPIPERIDINE BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |