Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 5/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435365 | 0.88 | TSHR (0.53) | LMNATSHRPGRVCAM1MAPT | |
| SCHEMBL2961542 | 0.82 | KCNJ1 (0.55) | LMNAPGRVCAM1MAPTALDH1A1 | |
| SCHEMBL4516641 | 0.82 | TSHR (0.64) | LMNATSHRPGRMAPTALDH1A1 | |
| SCHEMBL7838339 | 0.82 | LMNA (0.64) | LMNATSHRPGRMAPTALDH1A1 | |
| SCHEMBL6738366 | 0.82 | TSHR (0.76) | LMNATSHRPGRMAPTALDH1A1 | |
| Dinitrophenylene SCHEMBL27546949 | 0.81 | TSHR (0.63) | LMNATSHRVCAM1MAPTALDH1A1 | |
| SCHEMBL57152 | 0.80 | VCAM1 (0.64) | LMNATSHRVCAM1MAPTALDH1A1 | |
| SCHEMBL29913891 | 0.80 | VCAM1 (0.64) | LMNATSHRVCAM1MAPTALDH1A1 | |
| Dinitrophenylene SCHEMBL27524309 | 0.80 | TSHR (0.58) | LMNATSHRVCAM1ALDH1A1 | |
| SCHEMBL29526232 | 0.80 | TSHR (0.67) | LMNATSHRPGRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |