Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HA1 | P13674 | 2/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 9/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621792 | 0.86 | P4HTM (0.61) | P4HA1P4HTMMIFMAPTL3MBTL1 | |
| SCHEMBL27525392 | 0.83 | P4HTM (0.58) | P4HA1P4HTMMIFMAPTHCAR3 | |
| SCHEMBL7279218 | 0.81 | P4HA1 (0.54) | P4HA1P4HTMMIFMAPTHCAR3 | |
| SCHEMBL7279221 | 0.81 | P4HA1 (0.54) | P4HA1P4HTMMIFMAPTHCAR3 | |
| SCHEMBL17819955 | 0.79 | GABRA1 (0.47) | P4HTMMAPTL3MBTL1KDM4EHPGD | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL70231 | 0.77 | P4HTM (1.00) | P4HA1P4HTMMIFHCAR3L3MBTL1 | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL29363410 | 0.77 | P4HTM (1.00) | P4HA1P4HTMMIFHCAR3L3MBTL1 | |
| SCHEMBL3179541 | 0.76 | P4HTM (0.73) | P4HA1P4HTMMIFMAPTHCAR3 | |
| SCHEMBL840867 | 0.76 | HCAR3 (0.59) | P4HA1P4HTMMIFMAPTHCAR3 | |
| SCHEMBL22269020 | 0.76 | HCAR3 (0.59) | P4HA1P4HTMMIFMAPTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |