Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271098 | 0.79 | PPARG (0.49) | CA2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7276511 | 0.76 | HTR2C (0.38) | CA2CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL10650323 | 0.75 | HSD17B10 (0.49) | CA2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL7277465 | 0.73 | SLC6A3 (0.39) | CYP1A1CYP1A2CYP1B1SLC6A3SLC6A2 | |
| SCHEMBL7270932 | 0.73 | SLC6A3 (0.39) | CYP1A1CYP1A2CYP1B1SLC6A3SLC6A2 | |
| SCHEMBL7271513 | 0.73 | SLC6A3 (0.39) | CYP1A1CYP1A2CYP1B1SLC6A3SLC6A2 | |
| SCHEMBL7276707 | 0.71 | CA2 (0.41) | CA2CYP1A1CYP1A2CYP1B1SLC6A3 | |
| SCHEMBL10653418 | 0.70 | CA2 (0.53) | CA2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL7269675 | 0.69 | CA2 (0.40) | CA2SLC6A3SLC6A2LMNAALDH1A1 | |
| SCHEMBL7271620 | 0.67 | PIM1 (0.57) | CA2LMNAKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234860-A | — | — | None | — | — | JP | disclosed |
| JP-4234861-A | — | — | None | — | — | JP | disclosed |
| EP-0441539-B1 | Thiazine (or oxazine) derivatives and preparation thereof | TANABE SEIYAKU CO (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5496815-A | TREATMENT OF ISCHEMIC ENCEPHALOPATHIA | TANABE SEIYAKU CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5281592-A | Calcium antagonist, antiischemic agents, brains, nervous system disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-25 | — | — | US | disclosed |
| US-5246929-A | Prophylaxis or treatment of ischemic encephalopathia | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| JP-H04234860-A | THIAZINE (OR OXAZINE) DERIVATIVE, ITS PRODUCTION AND SYNTHETIC INTERMEDIATE THEREFOR | TANABE SEIYAKU CO LTD | 1992-08-24 | — | — | JP | disclosed |
| JP-H04234861-A | THIAZINE (OR OXAZINE) DERIVATIVE, ITS PRODUCTION AND SYNTHETIC INTERMEDIATE THEREFOR | TANABE SEIYAKU CO LTD | 1992-08-24 | — | — | JP | disclosed |
| EP-0441539-A2 | Thiazine (or oxazine) derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |