Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663807 | 0.84 | ALDH1A1 (0.63) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL15369211 | 0.82 | ALDH1A1 (0.41) | L3MBTL1POLBLMNANPC1SMN1; SMN2 | |
| SCHEMBL3221432 | 0.82 | GAA (0.53) | L3MBTL1LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL1970601 | 0.81 | L3MBTL1 (0.56) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL6974124 | 0.81 | L3MBTL1 (0.56) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL10039632 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL20117157 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL2906606 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL4259604 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL5606459 | 0.79 | ALDH1A1 (0.62) | L3MBTL1POLBLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526348-B1 | Indoline derivatives carrying an amide function, their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-02-18 | — | — | EP | disclosed |
| WO-1993003013-A1 | INDOLINE DERIVATIVES HAVING AN AMIDE FUNCTION, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELF SANOFI (FR) | 1993-02-18 | — | — | WO | disclosed |
| EP-0526348-A1 | Indoline derivatives carrying an amide function, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-02-03 | — | — | EP | disclosed |