Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974124 | 0.85 | L3MBTL1 (0.56) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL15071468 | 0.84 | POLB (0.57) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL5308413 | 0.82 | ALDH1A1 (0.41) | L3MBTL1POLBLMNANPC1SMN1; SMN2 | |
| SCHEMBL1970601 | 0.81 | L3MBTL1 (0.56) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL7277285 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL10039632 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL5606459 | 0.79 | ALDH1A1 (0.62) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL20117157 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNARAB9ANPC1 | |
| SCHEMBL4259604 | 0.79 | L3MBTL1 (0.54) | L3MBTL1POLBLMNACREBBPRAB9A | |
| SCHEMBL21159869 | 0.78 | ALDH1A1 (0.41) | L3MBTL1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212297-A1 | INHIBITORS OF PROTEIN KINASES | Ingenium Pharmaceuticals GmbH (DE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2010056827-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2009047359-A1 | INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2009-04-16 | — | — | WO | disclosed |
| EP-2038268-A2 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007148208-A2 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-27 | — | — | WO | disclosed |