Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528037 | 0.67 | LMNA (0.36) | LMNAHCAR2PARP1 | |
| SCHEMBL7641445 | 0.62 | CES1 (0.46) | LMNAHCAR2PARP1 | |
| SCHEMBL5239248 | 0.62 | KDM4E (0.44) | LMNAHCAR2PARP1 | |
| SCHEMBL20062514 | 0.61 | LMNA (0.43) | LMNAPARP1 | |
| SCHEMBL13629318 | 0.61 | KDM4E (0.45) | LMNAHCAR2PARP1 | |
| SCHEMBL11299370 | 0.61 | KDM4E (0.42) | LMNAHCAR2PARP1 | |
| SCHEMBL13629310 | 0.60 | ALDH1A1 (0.43) | LMNAHCAR2PARP1 | |
| SCHEMBL10528166 | 0.59 | HCAR2 (0.41) | LMNAHCAR2PARP1 | |
| SCHEMBL2290363 | 0.59 | MAPT (0.58) | LMNA | |
| SCHEMBL30061414 | 0.59 | LMNA (0.49) | LMNAHCAR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |