Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.59 |
| ▸ | MMP2 | P08253 | 11/20 | 0.59 |
| ▸ | MMP8 | P22894 | 6/20 | 0.59 |
| ▸ | MMP3 | P08254 | 6/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | MMP7 | P09237 | 3/20 | 0.59 |
| ▸ | FCER2 | P06734 | 2/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14900078 | 0.87 | ACE (0.63) | MMP2MMP9MMP7 | |
| SCHEMBL8138539 | 0.87 | ACE (0.63) | MMP2MMP9MMP7 | |
| SCHEMBL989841 | 0.86 | PSMB5 (0.64) | MMP1MMP2MMP8MMP3MMP7 | |
| SCHEMBL7066963 | 0.86 | MMP1 (0.61) | MMP1MMP2MMP8MMP3MMP9 | |
| SCHEMBL13956887 | 0.86 | PSMB5 (0.67) | MMP1MMP2MMP8MMP3MMP9 | |
| SCHEMBL7066966 | 0.86 | MMP1 (0.61) | MMP1MMP2MMP8MMP3MMP9 | |
| SCHEMBL15759462 | 0.86 | PSMB5 (0.64) | MMP1MMP2MMP8MMP3MMP7 | |
| SCHEMBL18862088 | 0.84 | FCER2 (0.57) | MMP1FCER2PSMB5 | |
| SCHEMBL7391831 | 0.83 | MMP1 (0.57) | MMP1MMP2MMP8MMP3MMP9 | |
| SCHEMBL17677127 | 0.83 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |