Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249330 | 0.84 | CCR1 (0.50) | CYP1A2UBE2NCHRM1FOLH1HPGD | |
| SCHEMBL620307 | 0.78 | CYP1A2 (0.64) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL10010707 | 0.77 | FOLH1 (0.69) | CYP1A2UBE2NCHRM1FOLH1CPA3 | |
| SCHEMBL7277645 | 0.75 | MTNR1A (0.55) | CYP1A2CPA3 | |
| Acetamide SCHEMBL7277641 | 0.72 | CYP1A2 (0.56) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL25218779 | 0.72 | ACHE (0.56) | HPGD | |
| SCHEMBL26730248 | 0.72 | HTR2A (0.53) | UBE2NCHRM1HTR2AHRH1TAAR1 | |
| SCHEMBL8572290 | 0.71 | CYP1A2 (0.55) | CYP1A2UBE2NFOLH1HPGDCPA3 | |
| SCHEMBL38656098 | 0.71 | CYP1A2 (0.59) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL6698882 | 0.71 | CYP1A2 (0.54) | CYP1A2UBE2NCHRM1FOLH1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |