Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269116 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL12405390 | 0.81 | LMNA (0.50) | NOTUMALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL7275808 | 0.79 | NOTUM (0.53) | NOTUMMAPTTP53 | |
| SCHEMBL7278038 | 0.78 | HTR3A (0.50) | ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL396467 | 0.75 | NOTUM (0.57) | NOTUMLMNAMEN1KMT2APAX8 | |
| SCHEMBL7278918 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL1548733 | 0.73 | NOTUM (0.68) | NOTUM | |
| SCHEMBL4179993 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| Hydrochloric Acid SCHEMBL7290643 | 0.72 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL1549100 | 0.72 | NOTUM (0.45) | NOTUMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |